Four Levels of Immune Response in Acute Infectious Diseases

Zheleznikova GF

Children Infection Research Institute, Ministry of Public Health Russia, St. Petersburg, Russia

Russ. J. Immunol. 2002, April, 7 (1), 25-32

The article presents the author’s concept of four levels of immune reactivity revealed in various acute infections. These four levels of immune response are different in cytokine production quantity, time of non-specific immunosuppression and the balance of cellular and humoral host defense forms. The explanation of this phenomenon seems to be in line with T helper cell heterogeneity (Th1, Th2, Th0).

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